- OWEN, IFAN (IEUAN) TUDUR (d. 1625?), a bard
- OWEN, Sir (HERBERT) ISAMBARD (1850 - 1927), medical man, scholar, and architect of universities
- OWEN, JAMES (1654 - 1706), Dissenting divine and tutor
- OWEN, JEREMY (fl. 1704-1744), Presbyterian minister and writer
- OWEN, JOHN (1836 - 1915), Calvinistic Methodist minister and author of the popular ballad 'Cân y Mochyn Du' ('the Ballad of the Black Pig')
- OWEN, JOHN (1854 - 1926), bishop
- OWEN, JOHN (1833 - 1896), cleric and author
- OWEN, JOHN (John Owen of Tyn-llwyn; 1807 - 1876), Calvinistic Methodist minister, and writer on agriculture
- OWEN, JOHN (1698 - 1755), chancellor of Bangor
- OWEN, JOHN (Owain Alaw; 1821 - 1883), musician
- OWEN, JOHN (1757 - 1829), writer on religious topics
- OWEN, JOHN (1733 - 1776), Methodist exhorter
- OWEN, JOHN (1616 - 1683), Puritan (Independent) divine
- OWEN, JOHN (d. 1759), poet, harpist, letter-writer
- OWEN, JOHN (1788 - 1867), cleric and author
- OWEN, JOHN (1790 - 1846), founder of Owens College, Manchester
- OWEN, Sir JOHN (1600 - 1666), royalist commander
- OWEN, JOHN (1564? - 1628?), epigrammatist
- OWEN, JOHN (1864 - 1953), minister (Presb. C.W.) and author
- OWEN, JOHN (1857 - 1934), preacher - see OWEN, RICHARD JONES
- OWEN, JOHN (1849 - 1917), pastor - see OWEN, JOHN
- OWEN, JOHN - see OWEN, OWEN JOHN
- OWEN, JOHN DYFNALLT (Dyfnallt; 1873 - 1956), minister (Congl.), poet, writer, journalist and Archdruid of Wales
- OWEN, JOHN JONES (1876 - 1947), musician
- OWEN, JOHN LEWIS - see OWEN, LEWIS
- OWEN, JOHNNY - see OWENS, JOHNNY RICHARD
- OWEN, JOSIAH (1711 - 1755), author - see OWEN, JEREMY
- OWEN, LEONARD (1890 - 1965), administrator in India, treasurer of the Honourable Society of Cymmrodorion
- OWEN, Baron LEWIS (d. 1555), judge
- OWEN, LEWIS (1572 - 1629?), anti-Romanist propagandist
- OWEN, LEWIS - see LEWIS, OWEN
- OWEN, LLEWELLYN ISAAC GETHIN MORGAN - see MORGAN-OWEN, LLEWELLYN ISAAC GETHIN
- OWEN, MARGARET (Peggy; 1742 - 1816)
- OWEN, MARGARET, heiress - see WYNN
- OWEN, MARGARET - see LLOYD GEORGE
- OWEN, MARY (1796 - 1875), hymn-writer
- OWEN, MARY ANNE (d. c. 1870), authoress - see OWEN, OWEN
- OWEN, MATTHEW (1631 - 1679) Llangar, Edeirnion, poet
- OWEN, MORFYDD LLWYN (1891 - 1918), composer, singer, and pianist
- OWEN, MORGAN (1585? - 1645), bishop
- OWEN, MORRIS BRYNLLWYN (1875 - 1949), minister (B), college professor, church historian
- OWEN, NICHOLAS (1752 - 1811), cleric and antiquary
- OWEN, OWEN (1850 - 1920), first chief inspector of the Central Welsh Board for Intermediate Education in Wales
- OWEN, OWEN (1806 - 1874), divine and physician
- OWEN, OWEN GRIFFITH (Alafon; 1847 - 1916), Calvinistic Methodist minister and poet
- OWEN, OWEN JOHN (1867 - 1960) y Fenni, printer and publisher, choir conductor and eisteddfod compère
- OWEN, PEGGY - see OWEN, MARGARET
- OWEN, RICHARD (1839 - 1887), revivalist, Calvinistic Methodist minister
- OWEN, RICHARD (fl. 1552), translator
- OWEN, RICHARD - see OWEN, RICHARD JONES