- E.O.J. - see JONES, EDWARD OWEN
- E.T. - see MORGAN, EDWARD
- EAMES, JANE MYFANWY - see EAMES, WILLIAM
- EAMES, MARION GRIFFITH (1921 - 2007), historical novelist
- EAMES, ROLANT (1750 - 1825), musician
- EAMES, WILLIAM (1874 - 1958), journalist
- EBEN FARDD - see THOMAS, EBENEZER
- EDDOWES, JOSHUA (1724 - 1811), printer and bookseller
- EDDOWES, WILLIAM (1754), printer - see EDDOWES, JOSHUA
- EDERN DAFOD AUR, made a small dosbarth (arrangement or grammar) of the orthography of the Welsh language and of the form of words
- EDEYRN ap NUDD - see HUGHES, JOHN WILLIAM
- EDEYRN o FÔN - see HUGHES, JOHN WILLIAM
- EDGEWORTH, ROGER (d. 1560), Roman Catholic divine
- EDISBURY family Bedwal, Marchwiel, Pentre-clawdd, Erddig,
- EDMONDES, CHARLES GRESFORD (1838 - 1893), archdeacon and college principal
- EDMONDES, FREDERICK WILLIAM (1841 - 1918), Archdeacon of Llandaff - see EDMONDES, CHARLES GRESFORD
- EDMONDES, THOMAS (1806 - 1892), vicar - see EDMONDES, CHARLES GRESFORD
- EDMUND-DAVIES, HERBERT EDMUND (1906 - 1992), lawyer and judge
- EDMUNDS, MARY ANNE (1813 - 1858), teacher
- EDMUNDS, WILLIAM (1827 - 1875), cleric, schoolmaster, and man of letters
- EDMWND LLWYD Glynllifon (d. 1541) - see GLYN
- EDNYFED - see EVANS, FREDERICK
- EDNYFED ap CYNWRIG - see EDNYFED FYCHAN
- EDNYFED FYCHAN, noble family of Gwynedd
- EDNYFED, SION, musician
- EDNYFED, WILLIAM, 'crowder'
- EDWARD ab IFAN, harpist
- EDWARD ap HUMPHREY Maes-y-neuadd (d. 1620) - see WYNN
- EDWARD ap HYWEL ap GRUFFYDD (fl. 15th century), writer of cywyddau
- EDWARD ap ROGER (fl. 16th century), collector of manuscripts and poet
- EDWARD GRYTHOR, 'crowder.'
- EDWARD MAELOR (fl. c. 1580-1620), poet
- EDWARD, DAFYDD, poet - see DAFYDD, EDWARD
- EDWARD, JOHN WYN Bodewryd (d. 1614) - see WYNN
- EDWARDES, Kensington - see EDWARDS
- EDWARDES, Chirkland - see EDWARDS
- EDWARDES, DAVID (c. 1630 - 1690), landowner and deputy-herald
- EDWARDES, DAVID EDWARD (1832 - 1898), translator
- EDWARDS family Cilhendre, Plas Yolyn,
- EDWARDS family Stansty,
- EDWARDS, Kensington - see EDWARDS
- EDWARDS, Sir FRANCIS (1852 - 1927), baronet and M.P.
- EDWARDS family Chirkland,
- EDWARDS, ALFRED GEORGE (1848 - 1937), first archbishop of Wales
- EDWARDS, ARTHUR TRYSTAN (1884 - 1973), architect and pioneer town planner
- EDWARDS, ARTHUR TUDOR (1890 - 1946), surgeon
- EDWARDS, CHARLES (1628 - after 1691), Puritan man of letters
- EDWARDS, CHARLES ALFRED (1882 - 1960), metallurgist and principal of University College of Swansea
- EDWARDS, DAVID (1660 - 1716), Independent minister
- EDWARDS, DAVID (1858 - 1916), journalist