- POWEL, DANIEL (fl. 1612), layman - see POWEL, DAVID
- POWEL, DAVID (c.1540 - 1598), cleric and historian
- POWEL, GABRIEL (1576 - 1611), rector - see POWEL, DAVID
- POWEL, JOHN (d. 1767), weaver-poet
- POWEL, LEWYS - see LEWYS ap HYWEL
- POWEL, MORGAN (fl. c. 1563), poet, one of the Glamorgan writers of cwndidau, a cleric of Llanhari
- POWEL, RICHARD - see POWELL, RICHARD
- POWEL, SAMUEL (1570 - 1600), vicar - see POWEL, DAVID
- POWEL, SION - see POWEL, JOHN
- POWEL, THOMAS (1845 - 1922), Celtic scholar
- POWEL, WATCYN (c. 1600 - 1655) Pen-y-fai, Tir Iarll, gentleman, bard, and genealogist
- POWELL family Nanteos, Llechwedd-dyrus,
- POWELL, ANNIE (1906 - 1986), teacher, local politician and Communist mayor of Rhondda
- POWELL, DAVID (d. 1781), Franciscan friar
- POWELL, EDWARD (1478? - 1540), Roman Catholic theologian
- POWELL, EVAN (1721 - 1785), carpenter who wrote verse
- POWELL, GRIFFITH (1561 - 1620), principal of Jesus College, Oxford
- POWELL, HANNAH (1729 - 1805), matron of 'Trevecka Family' - see LLOYD, SIMON
- POWELL, HOWELL (1819 - 1875), Calvinistic Methodist minister in the U.S.A., and author
- POWELL, HOWELL (d. 1716), Congregational minister
- POWELL, JOHN
- POWELL, Sir JOHN (1633 - 1696), lawyer and judge
- POWELL, JONATHAN (1764 - 1823), Independent minister
- POWELL, LEWIS (1788 - 1869), Independent minister
- POWELL, PHILIP (1594 - 1646), O.S.B.
- POWELL, RAY - see POWELL, RAYMOND
- POWELL, RAYMOND (1928 - 2001), Labour politician
- POWELL, RICE (fl. 1641-1665), colonel in the Parliamentary army
- POWELL, RICHARD (1769 - 1795), poet and schoolmaster
- POWELL, THOMAS (1779? - 1863), coal-owner
- POWELL, THOMAS, chartist
- POWELL, THOMAS (1608? - 1660), cleric
- POWELL, THOMAS (1781 - 1842), Congregational minister and author
- POWELL, THOMAS (1572? - 1635?), attorney and author
- POWELL, VAVASOR (1617 - 1670), Puritan divine
- POWELL, WILLIAM (Gwilym Pennant; 1830 - 1902), poet
- POWELL, WILLIAM EIFION (1934 - 2009), minister (Cong.) and college principal
- POWIS, Earls of - see HERBERT
- POWYS, JOHN COWPER (1872 - 1963), novelist, poet, literary critic and popular philosopher
- POWYS, Lords of - see GREY
- POYER, JOHN (d. 1649) Pembroke, mayor
- PREECE, Sir WILLIAM HENRY (1834 - 1913), electrical engineer
- PRENDERGAST, ANNE (d. 1770), heiress - see WILLIAMS
- PRICAEUS, JOHN - see PRICE, JOHN
- PRICE family Rhiwlas,
- PRICE THOMAS, CLEMENT (1893 - 1973), pioneering surgeon
- PRICE, BENJAMIN (1804 - 1896), first bishop of the 'Free Church of England'
- PRICE, BENJAMIN (Cymro Bach; 1792 - 1854), Baptist minister and littérateur
- PRICE, CHARLES (d. 1646) Pilleth,, soldier and politician
- PRICE, CHRISTOPHER (d. 1697), apothecary, preacher, free-communion Baptist